Individualised medicine

N-of-1 trials and citizen science

Why the research that guides medicine is built on the average of many people — and what it means to become the scientist studying the only patient who is actually you.

The practice of medicine

Guidelines, automation, and personalised medicine

A general practitioner's account of how medicine was quietly automated — and what a small independent practice can do to keep it personal.

Physiology

The vagus nerve and heart rate variability

The nerve that links mind and body, and why the tiny beat-to-beat variation in a heartbeat has become one of the more useful windows onto an individual's health.

Physiology

Vascular health: what holds the blood

Blood vessels are not passive plumbing. What they sense, how they harden, and how vascular health can be measured in the clinic.